Biopsy proven cirrhosis
Documented portal hypertension,
Episodes of past upper GI bleeding attributed to portal
hypertension
Prior episodes of hepatic failure / encephalopathy /
coma.
NYHA Class IV
Chronic restrictive, obstructive or
vascular disease resulting in severe exercice restriction,
i.e. unable to climb stairs or perform household duties.
Documented chronic hypoxia, hypercapnia, secondary
polycythemia , severe pulmonary hypertension (> 40 mmHg),
or respirator dependency.
Receiving chronic dialysis
The patient has received therapy that
suppresses resistance to infection e.g. immuno-suppression,
chemotherapy, radiation, long term or recent hight dose
steroids, or has a disease that is sufficiently advanced to
suppress resistance to infection, e.g. leukemia, lymphoma,
AIDS.